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RXFP1 receptor agonist-8

RXFP1 receptor agonist-8 (Example 2) is a RXFP1 receptor agonist. RXFP1 receptor agonist-8 stimulates cAMP production in HEK293 cells stably expressing human RXFP1, with an EC50 value of 1.8 nM[1].

Product Specifications

CAS Number

[2941271-76-5]

UNSPSC

12352005

Target

RXFP Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/rxfp1-receptor-agonist-8.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=C(C(NC2=CC=C(F)C(C(F)(F)F)=C2)=O)C=C(CCCC3)C3=C1)C4=CC(C5=C(F)C=CC(C(C(O)=O)NC(C6CCOCC6)=O)=C5)=CC=C4OC

Molecular Formula

C40H36F5N3O7

Molecular Weight

765.72

References & Citations

[1]Jones, Clifford D., et al. Prepration of pyridopyrimidines as KRAS mutant proteins inhibitors useful in treatment of cancers. Patent. WO2022248885.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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