RXFP1 receptor agonist-8

RXFP1 receptor agonist-8 (Example 2) is a RXFP1 receptor agonist. RXFP1 receptor agonist-8 stimulates cAMP production in HEK293 cells stably expressing human RXFP1, with an EC50 value of 1.8 nM[1].

Product Specifications

CAS Number

[2941271-76-5]

UNSPSC

12352005

Target

RXFP Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/rxfp1-receptor-agonist-8.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=C(C(NC2=CC=C(F)C(C(F)(F)F)=C2)=O)C=C(CCCC3)C3=C1)C4=CC(C5=C(F)C=CC(C(C(O)=O)NC(C6CCOCC6)=O)=C5)=CC=C4OC

Molecular Formula

C40H36F5N3O7

Molecular Weight

765.72

References & Citations

[1]Jones, Clifford D., et al. Prepration of pyridopyrimidines as KRAS mutant proteins inhibitors useful in treatment of cancers. Patent. WO2022248885.