5-HT2 agonist-1 (free base)

5-HT2 agonist-1 (Compound 24) free base is a 5-HT2A & 5-HT2B & 5-HT2C agonist, with IC50s of 10 nM, 8.3, and 1.6 nM respectively. 5-HT2 agonist-1 free base can be used for research of depression, alcoholism, tobacco and cocaine addiction, inflammation, cluster headache, PTSD, seizure disorders and other CNS disorders[1].

Product Specifications

CAS Number

[2708279-77-8]

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/5-ht2-agonist-1-free-base.html

Solubility

10 mM in DMSO

Smiles

OC1=CC=CC2=C1C(CCNCC3=C(OC)C=CC=C3)=CN2C

Molecular Formula

C19H22N2O2

Molecular Weight

310.39

References & Citations

[1]Alan Kozikowski, et al. 3- (2- (aminoethyl) -indol-4-ol derivatives, methods of preparation thereof, and the use as 5-ht2 receptor modulators. Patent. WO2021179091.