5-HT2C agonist-3 (free base)
5-HT2C agonist-3 ((+) -19) free base is a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM) . 5-HT2C agonist-3 free base has antipsychotic drug-like activity. 5-HT2C agonist-3 free base blocks Amphetamine-induced hyperactivity[1].
Product Specifications
CAS Number
[2104810-17-3]
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/5-ht2c-agonist-3-free-base.html
Solubility
10 mM in DMSO
Smiles
COC(C=CC=C1)=C1CNC[C@@H]2[C@@H](C3=C(C=CC(F)=C3)OC)C2
Molecular Formula
C19H22FNO2
Molecular Weight
315.38
References & Citations
[1]Guiping Zhang, et al. Discovery of N-Substituted (2-Phenylcyclopropyl) methylamines as Functionally Selective Serotonin 2C Receptor Agonists for Potential Use as Antipsychotic Medications. J. Med. Chem. 2017, 60, 14, 6273–6288.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor
Curated Selection
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