PHD-IN-2
PHD-IN-2 (Compound 91) is a PHD antagonist (IC50: EC50: [1].
Product Specifications
CAS Number
[2924182-42-1]
UNSPSC
12352005
Target
HIF/HIF Prolyl-Hydroxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/phd-in-2.html
Solubility
10 mM in DMSO
Smiles
N#CC1=NC=C(CNC(C2=NC=C3N=C(N4CC5(C4)CN(C5)C(OC(C)(C)C)=O)C=CC3=C2O)=O)C=C1
Molecular Formula
C26H27N7O4
Molecular Weight
501.54
References & Citations
[1]Xiao DING, et al. Prolyl hydroxylase domain-containing protein (phd) inhibitors and uses thereof. Patent. US20230192723A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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