Immunosuppressant-1
Immunosuppressant-1 (Compound 31) inhibits anti-CD3/anti-CD28 co-stimulated T-cell proliferation. Immunosuppressant-1 has immunosuppressive activity, and induces apoptosis by activating caspase-3 and PARP in activated lymph node cells[1].
Product Specifications
CAS Number
[1224571-03-2]
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/immunosuppressant-1.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C(/C(CC2=CC=C(Br)C=C2)=N/O)C=C1O
Molecular Formula
C14H12BrNO3
Molecular Weight
322.15
References & Citations
[1]Li HQ, et al. Design, synthesis, and immunosuppressive activity of new deoxybenzoin derivatives. ChemMedChem. 2010 Jul 5;5 (7) :1117-22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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