7Ethanol-10NH2-11F-Camptothecin
7Ethanol-10NH2-11F-Camptothecin is a Camptothecin (HY-16560) analogue that serves as an ADC cytotoxin for the synthesis of antibody-drug conjugates (ADCs) . 7Ethanol-10NH2-11F-Camptothecin can inhibit tumor growth and is used in cancer research[1].
Product Specifications
CAS Number
[2873460-31-0]
UNSPSC
12352203
Target
ADC Payload; Topoisomerase
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/7ethanol-10nh2-11f-camptothecin.html
Solubility
10 mM in DMSO
Smiles
O=C1N2C(C(C(C2)=C(C3=C4)CO)=NC3=CC(F)=C4N)=CC5=C1COC([C@]5(O)CC)=O
Molecular Formula
C21H18FN3O5
Molecular Weight
411.38
References & Citations
[1]Petersen, M. E, et al. Camptothecin analogues, conjugates and methods of use. WO2022246576 A1.2022-01-12.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
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