MC-GGFG-AM- (10NH2-11F-Camptothecin)
MC-GGFG-AM- (10NH2-11F-Camptothecin) is an antibody drug conjugates (ADC) . MC-GGFG-AM- (10NH2-11F-Camptothecin) binds to the anti-TROp-2 antibody sacituzumab via a hydrolysable pH-sensitive linker and has anti-tumor activity. MC-GGFG-AM- (10NH2-11F-Camptothecin) can be used for cancer research[1].
Product Specifications
CAS Number
2987938-97-4
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mc-ggfg-am-10nh2-11f-camptothecin.html
Solubility
10 mM in DMSO
Smiles
O=C1N2C(C(C(C2)=CC3=C4)=NC3=CC(F)=C4NC(CNC([C@@H](NC(CNC(CNC(CCCCCN5C(C=CC5=O)=O)=O)=O)=O)CC6=CC=CC=C6)=O)=O)=CC7=C1COC([C@]7(O)CC)=O
Molecular Formula
C45H45FN8O11
Molecular Weight
892.88
References & Citations
[1]Petersen, M. E, et al. Camptothecin analogues, conjugates and methods of use. WO2022246576 A1.2022-01-12.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Frequently Asked Questions
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