HPK1-IN-37
HPK1-IN-37 (compound A85) is an inhibitor of HPK1 (IC50=3.7 nM) . HPK1-IN-37 can be used for research in HPK1 related disorders or diseases including cancers[1].
Product Specifications
CAS Number
2766481-68-7
UNSPSC
12352005
Target
MAP4K
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hpk1-in-37.html
Solubility
10 mM in DMSO
Smiles
CN(CC1)CCC1N(N=C2)C=C2OC(N=C3C4=CC(C5(O)COC5)=CC(N6[C@@H](CCC6)CO)=C4)=C(N=C3)N
Molecular Formula
C27H35N7O4
Molecular Weight
521.61
References & Citations
[1]Xu S, et al. Preparation of 3-[ (1H-pyrazol-4-yl) oxy]pyrazin-2-amine compounds as HPK1 inhibitor and application. World Intellectual Property Organization, WO2022068848 A1. 2022-04-07.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV672229 1.0 µg DNA
PPIG Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details 
249523-Biotin 100 µL
NTS (neurotensin, NMN-125, NN, NT, NT/N, NTS1) (Biotin)
Sign In for Pricing
View Details