HPK1-IN-37
HPK1-IN-37 (compound A85) is an inhibitor of HPK1 (IC50=3.7 nM) . HPK1-IN-37 can be used for research in HPK1 related disorders or diseases including cancers[1].
Product Specifications
CAS Number
2766481-68-7
UNSPSC
12352005
Target
MAP4K
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hpk1-in-37.html
Solubility
10 mM in DMSO
Smiles
CN(CC1)CCC1N(N=C2)C=C2OC(N=C3C4=CC(C5(O)COC5)=CC(N6[C@@H](CCC6)CO)=C4)=C(N=C3)N
Molecular Formula
C27H35N7O4
Molecular Weight
521.61
References & Citations
[1]Xu S, et al. Preparation of 3-[ (1H-pyrazol-4-yl) oxy]pyrazin-2-amine compounds as HPK1 inhibitor and application. World Intellectual Property Organization, WO2022068848 A1. 2022-04-07.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
