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HDAC6-IN-25

Product Specifications

UNSPSC Description

HDAC6-IN-25 (compound 8) is a selective inhibitor of HDAC6, with the IC50 of 0.6 nM[1].

Target Antigen

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage;Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hdac6-in-25.html

Solubility

10 mM in DMSO

Smiles

O=S1(C2=C(C=CC=C2)C=CC3=CC=C(C(NO)=O)C=C13)=O

Molecular Weight

301.32

References & Citations

[1]Shawn J. Stachel, et al. Virtual screening for early identification of potent and selective histone deacetylase 6 inhibitor series. Bioorganic & Medicinal Chemistry Letters Volume 96, 15 November 2023, 129537

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-156472/HDAC6-IN-25-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-156472/

Clinical Information

No Development Reported

Curated Selection

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