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RIOK2-IN-2

RIOK2-IN-2 (8) is a RIOK2 inhibitor, with IC50 values of 3.02 μM and 5.34 μM in MKN-1 and MOLT4 cells, respectively[1].

Product Specifications

CAS Number

[2648987-17-9]

UNSPSC

12352005

Target

Ser/Thr Kinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/riok2-in-2.html

Solubility

10 mM in DMSO

Smiles

O=C1NC2=CC=C(C3=CC=C(OC)N=C3)C=C2C4=C1C=NN4C5=CC=C(N6CCNCC6)C(C(F)(F)F)=C5

Molecular Formula

C27H23F3N6O2

Molecular Weight

520.51

References & Citations

[1]Huilan Xiong, et al. Exploration of tricyclic heterocycles as core structures for RIOK2 inhibitors. RSC Med Chem. 2023 Jul 21;14 (10) :2007-2011.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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