RIOK2-IN-2
RIOK2-IN-2 (8) is a RIOK2 inhibitor, with IC50 values of 3.02 μM and 5.34 μM in MKN-1 and MOLT4 cells, respectively[1].
Product Specifications
CAS Number
[2648987-17-9]
UNSPSC
12352005
Target
Ser/Thr Kinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/riok2-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C1NC2=CC=C(C3=CC=C(OC)N=C3)C=C2C4=C1C=NN4C5=CC=C(N6CCNCC6)C(C(F)(F)F)=C5
Molecular Formula
C27H23F3N6O2
Molecular Weight
520.51
References & Citations
[1]Huilan Xiong, et al. Exploration of tricyclic heterocycles as core structures for RIOK2 inhibitors. RSC Med Chem. 2023 Jul 21;14 (10) :2007-2011.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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