Topoisomerase I inhibitor 9
Selected Variant
HY-156462
Size: 1 Each
Topoisomerase I inhibitor 9 (compound 3d) is a leishmanial topoisomerase IB inhibitor. Topoisomerase I inhibitor 9 has antileishmanial activity against L. donovani promastigotes, with the IC50 of 34.81μM[1].
Product Specifications
CAS Number
1228150-86-4
UNSPSC
12352005
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/topoisomerase-i-inhibitor-9.html
Solubility
10 mM in DMSO
Smiles
FC1=CC=C(C(C2=CNC3=C2C=C(Br)C=C3)C4=CNC5=C4C=C(Br)C=C5)C=C1
Molecular Formula
C23H15Br2FN2
Molecular Weight
498.19
References & Citations
[1]Kour P, et al. Design, synthesis, and biological evaluation of 3,3'-diindolylmethane N-linked glycoconjugate as a leishmanial topoisomerase IB inhibitor with reduced cytotoxicity. RSC Med Chem. 2023;14 (10) :2100-2114. Published 2023 Aug 30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Price
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