T-1-MCPAB
T-1-MCPAB is a VEGFR-2 inhibitor (IC50=0.135 µM) that effectively inhibits MCF7 migration. T-1-MCPAB can be used in cancer research[1].
Product Specifications
UNSPSC
12352005
Target
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/t-1-mcpab.html
Solubility
10 mM in DMSO
Smiles
CN(C(N1CC(NC2=CC=C(C(NC3=CC=CC(Cl)=C3)=O)C=C2)=O)=O)C(N=CN4C)=C4C1=O
Molecular Formula
C22H19ClN6O4
Molecular Weight
466.88
References & Citations
[1]Eissa IH, et al. Anti-breast cancer potential of a new xanthine derivative: In silico, antiproliferative, selectivity, VEGFR-2 inhibition, apoptosis induction and migration inhibition studies. Pathol Res Pract. 2023 Nov;251:154894.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
VEGFR2/KDR/Flk-1
Frequently Asked Questions
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