ERK5-IN-6
ERK5-IN-6 (compound 5J) is an ERK5 kinase inhibitor with anticancer activity. ERK5-IN-6 exhibits good anti-proliferative activity with the IC50 value of 4.56 µg/mL for A549 cells[1].
Product Specifications
CAS Number
2734916-64-2
UNSPSC
12352005
Target
ERK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/erk5-in-6.html
Solubility
10 mM in DMSO
Smiles
C12=NC=CC=C1C(C3=CCN(CC4=CC=C5C=CC=CC5=C4)CC3)=CN2
Molecular Formula
C23H21N3
Molecular Weight
339.43
References & Citations
[1]Qin Zhang, et al. Design, synthesis and SAR of novel 7-azaindole derivatives as potential Erk5 kinase inhibitor with anticancer activity. Bioorg Med Chem. 2023 Oct 14:95:117503.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERK
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