Anti-inflammatory agent 61

Anti-inflammatory agent 61 (Compound 5b) is a potent anti-inflammatory agent. Anti-inflammatory agent 61 reduces TNF-α expression in LPS-induced inflammation in RAW 264.7 cells. Anti-inflammatory agent 61 alleviates APAP-induced inflammation in HepG2 cells[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

TNF Receptor

Type

Reference compound

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-inflammatory-agent-61.html

Solubility

10 mM in DMSO

Smiles

O=C(COC([C@@]1(C2CC[C@@]3(C([C@]2(CC[C@H]1OC(C)=O)C)C(C=C4C5[C@H]([C@@H](CC[C@@]5(CC[C@]43C)C)C)C)=O)C)C)=O)OC6=C(C(C)C)C=CC(C)=C6

Molecular Formula

C44H62O7

Molecular Weight

702.96

References & Citations

[1]Elgazar AA, et al. 3-Acetyl-11-keto-β-boswellic Acid-Based Hybrids Alleviate Acetaminophen-Induced Hepatotoxicity in HepG2 by the Regulation of Inflammatory and Oxidative Stress Pathways: An Integrated Approach. ACS Omega. 2023 Oct 12;8 (42) :39490-39510.