NOX2-IN-2
Product Specifications
UNSPSC Description
NOX2-IN-2 (compound 33) is a potent NOX2 inhibitor targeting the p47phox-p22phox protein-protein interaction with a Ki of 0.24 μM. NOX2-IN-2 inhibits ROS production derived from NOX2 in cells[1].
Target Antigen
NADPH Oxidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nox2-in-2.html
Solubility
10 mM in DMSO
Smiles
NC1=NC2=CC=C(C=C2C=C1)OCC3=CN(N=N3)CCOCCOC4=CC=C5N=C(C=CC5=C4)N
Molecular Weight
471.51
References & Citations
[1]Jie Zang, et al.Targeting NOX2 with Bivalent Small-Molecule p47phox-p22phox Inhibitors. J Med Chem. 2023 Oct 19.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-156425/NOX2-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-156425/
Clinical Information
No Development Reported
CAS Number
2648709-79-7
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1236707-01 0.02 mg (E-Coli)
Recombinant Clostridium botulinum ATP synthase subunit beta (atpD)
Ask
View Details 
MBS1236707-02 0.02 mg (Yeast)
Recombinant Clostridium botulinum ATP synthase subunit beta (atpD)
Ask
View Details MBS1236707-03 0.1 mg (E-Coli)
Recombinant Clostridium botulinum ATP synthase subunit beta (atpD)
Ask
View Details