LtaS-IN-2
LtaS-IN-2 (compound 13) is a inhibitor of LTA synthesis, and shows antibacterial activity against S. aureus and S. epidermidis, with the MIC90 of 0.5 μg/mL and 1 μg/mL, respectively. LtaS-IN-2 is a derivative of LtaS-IN-1.
Product Specifications
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ltas-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C(CC1=COC2=CC=C3C=CC=CC3=C21)OCC(NC4=NN=C(O4)C5=CC=C(C=C5)S(F)(F)(F)(F)F)=O
Molecular Formula
C24H16F5N3O5S
Molecular Weight
553.46
References & Citations
[1]Douglas EJA, Marshall B, Alghamadi A, et al. Improved Antibacterial Activity of 1,3,4-Oxadiazole-Based Compounds That Restrict Staphylococcus aureus Growth Independent of LtaS Function [published online ahead of print, 2023 Oct 13]. ACS Infect Dis. 2023;10.1021/acsinfecdis.3c00250.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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