AuM1Gly
AuM1Gly is a topoisomerase I inhibitor. AuM1Gly affects the growth of MDA-MB-231 breast cancer cells, with IC50 values in the low nanomolar range[1].
Product Specifications
UNSPSC
12352005
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aum1gly.html
Solubility
10 mM in DMSO
Smiles
OC(C1=CC=CC=C1)CN(C2[Au]OC(CNC(OC(C)(C)C)=O)=O)C(Cl)=C(N2C)Cl
Molecular Formula
C19H24AuCl2N3O5
Molecular Weight
642.28
References & Citations
[1]Domenico Iacopetta, et al. NHC-Ag (I) and NHC-Au (I) Complexes with N-Boc-Protected α-Amino Acidate Counterions Powerfully Affect the Growth of MDA-MB-231 Cells.ACS Med. Chem. Lett. 2023, RETURN TO ARTICLES ASAPPREVLETTERNEXT
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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