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AuM1Gly

AuM1Gly is a topoisomerase I inhibitor. AuM1Gly affects the growth of MDA-MB-231 breast cancer cells, with IC50 values in the low nanomolar range[1].

Product Specifications

UNSPSC

12352005

Target

Topoisomerase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/aum1gly.html

Solubility

10 mM in DMSO

Smiles

OC(C1=CC=CC=C1)CN(C2[Au]OC(CNC(OC(C)(C)C)=O)=O)C(Cl)=C(N2C)Cl

Molecular Formula

C19H24AuCl2N3O5

Molecular Weight

642.28

References & Citations

[1]Domenico Iacopetta, et al. NHC-Ag (I) and NHC-Au (I) Complexes with N-Boc-Protected α-Amino Acidate Counterions Powerfully Affect the Growth of MDA-MB-231 Cells.ACS Med. Chem. Lett. 2023, RETURN TO ARTICLES ASAPPREVLETTERNEXT

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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