KR-27425

AChE activator 1 (compound 13) is a non-pyridinium oxime reactivator of paraoxon-inhibited acetylcholinesterase (AChE) [1].

Product Specifications

UNSPSC

12352211

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/kr-27425.html

Solubility

10 mM in DMSO

Smiles

CC(CCCNCCNC(/C=N/O)=O)C

Molecular Formula

C10H21N3O2

Molecular Weight

215.29

References & Citations

[1]Vishakantegowda AG, et al. Discovery of (E) -2- (hydroxyimino) -N- (2 ((4methylpentyl) amino) ethyl) acetamide (KR-27425) as a non-pyridinium oxime reactivator of paraoxon-inhibited acetylcholinesterase [published online ahead of print, 2023 Oct 12]. Bioorg Med Chem Lett. 2023;96:129504.