KR-27425
AChE activator 1 (compound 13) is a non-pyridinium oxime reactivator of paraoxon-inhibited acetylcholinesterase (AChE) [1].
Product Specifications
UNSPSC
12352211
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/kr-27425.html
Solubility
10 mM in DMSO
Smiles
CC(CCCNCCNC(/C=N/O)=O)C
Molecular Formula
C10H21N3O2
Molecular Weight
215.29
References & Citations
[1]Vishakantegowda AG, et al. Discovery of (E) -2- (hydroxyimino) -N- (2 ((4methylpentyl) amino) ethyl) acetamide (KR-27425) as a non-pyridinium oxime reactivator of paraoxon-inhibited acetylcholinesterase [published online ahead of print, 2023 Oct 12]. Bioorg Med Chem Lett. 2023;96:129504.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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