α-Amylase/α-Glucosidase-IN-6

α-Amylase/α-Glucosidase-IN-6 (compound 5j) is a potent dual inhibitor of α-amylase and α-glucosidase, with IC50s of 17.0 and 40.1 µM, respectively. α-Amylase/α-Glucosidase-IN-6 exhibits anti-hyperglycemic activities[1].

Product Specifications

UNSPSC

12352005

Target

Amylases; Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/α-amylase-α-glucosidase-in-6.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC=CC=C1C2=NOC(COC3=NC4=CC=C(OC)C=C4N=C3NCC)=C2

Molecular Formula

C21H19ClN4O3

Molecular Weight

410.85

References & Citations

[1]Phongphane L, et, al. Synthesis, biological evaluation, and molecular modelling of novel quinoxaline-isoxazole hybrid as anti-hyperglycemic. Comput Biol Chem. 2023 Oct:106:107938.