α-Amylase/α-Glucosidase-IN-6
α-Amylase/α-Glucosidase-IN-6 (compound 5j) is a potent dual inhibitor of α-amylase and α-glucosidase, with IC50s of 17.0 and 40.1 µM, respectively. α-Amylase/α-Glucosidase-IN-6 exhibits anti-hyperglycemic activities[1].
Product Specifications
UNSPSC
12352005
Target
Amylases; Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/α-amylase-α-glucosidase-in-6.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=CC=C1C2=NOC(COC3=NC4=CC=C(OC)C=C4N=C3NCC)=C2
Molecular Formula
C21H19ClN4O3
Molecular Weight
410.85
References & Citations
[1]Phongphane L, et, al. Synthesis, biological evaluation, and molecular modelling of novel quinoxaline-isoxazole hybrid as anti-hyperglycemic. Comput Biol Chem. 2023 Oct:106:107938.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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