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AChE-IN-44

AChE-IN-44 (Compound Tap4) is an AChE inhibitor. AChE-IN-44 can be converted into the thiazole salt AChE inhibitor Tat2[1].

Product Specifications

CAS Number

[2758685-58-2]

UNSPSC

12352005

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ache-in-44.html

Solubility

10 mM in DMSO

Smiles

O=CN(CC1=CC=CC=C1)/C(C)=C(SSCCC(C)C)\CCNC2=C(CCCC3)C3=NC4=CC(Cl)=CC=C42

Molecular Formula

C31H38ClN3OS2

Molecular Weight

568.24

References & Citations

[1]Liu C, et al. Discovery of thiazole salt AChE inhibitors and development of thiamine disulfide prodrugs targeting the central nervous system. Bioorg Chem. 2023 Oct;139:106702.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

AChE

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