Xanthine oxidase-IN-12
Xanthine oxidase-IN-12 (Compound 11) is a xanthine oxidase (XO) inhibitor with an IC50 of 91 nM. Xanthine oxidase-IN-12 also has antioxidant activity and reduces intracellular ROS[1].
Product Specifications
CAS Number
3041062-80-7
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS) ; Xanthine Oxidase
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/xanthine-oxidase-in-12.html
Solubility
10 mM in DMSO
Smiles
O=C1OC2=C(C(O)=CC(O)=C2)C=C1C3=CC=CC(Br)=C3
Molecular Formula
C15H9BrO4
Molecular Weight
333.13
References & Citations
[1]Fais A, et al. Design of 3-Phenylcoumarins and 3-Thienylcoumarins as Potent Xanthine Oxidase Inhibitors: Synthesis, Biological Evaluation, and Docking Studies. ChemMedChem. 2023 Oct 6:e202300400.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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