Anti-inflammatory agent 59
Product Specifications
UNSPSC Description
Anti-inflammatory agent 59 is an anti-inflammatory agent. Anti-inflammatory agent 58 inhibits IL-1β with an IC50 of 2.28 μM. Anti-inflammatory agent 58 decreases pro-inflammatory gene expression, protein secretion, and NF-κB phosphorylation[1].
Target Antigen
Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-inflammatory-agent-59.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@@H](O)CO[C@@H]1CN2C=NC3=C(NCC4=CC=CC(I)=C4)N=CN=C23
Molecular Weight
467.26
References & Citations
[1]Nguyen M, et al. Design and Synthesis of l-1'-Homologated Adenosine Derivatives as Potential Anti-inflammatory Agents. ACS Omega. 2023 Sep 19;8(39):36361-36369.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-156342/Anti-inflammatory-agent-59-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-156342/
Clinical Information
No Development Reported
CAS Number
9007-83-4
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