Anti-inflammatory agent 58

Anti-inflammatory agent 58 is an anti-inflammatory agent. Anti-inflammatory agent 58 inhibits IL-1β with an IC50 of 1.08 μM. Anti-inflammatory agent 58 decreases pro-inflammatory gene expression, protein secretion, and NF-κB phosphorylation[1].

Product Specifications

CAS Number

[3032851-09-2]

UNSPSC

12352005

Target

Interleukin Related

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-inflammatory-agent-58.html

Solubility

10 mM in DMSO

Smiles

O[C@H]1[C@@H](O)CO[C@@H]1CN2C=NC3=C(NCC4=CC=CC(Br)=C4)N=CN=C23

Molecular Formula

C17H18BrN5O3

Molecular Weight

420.26

References & Citations

[1]Nguyen M, et al. Design and Synthesis of l-1'-Homologated Adenosine Derivatives as Potential Anti-inflammatory Agents. ACS Omega. 2023 Sep 19;8 (39) :36361-36369.