BCN-exo-PEG2-maleimide

BCN-exo-PEG2-maleimide is an ADC Linker containing 2 PEG units. BCN-exo-PEG2-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.

Product Specifications

CAS Number

[2141976-22-7]

UNSPSC

12352203

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bcn-exo-peg2-maleimide.html

Solubility

10 mM in DMSO

Smiles

O=C(C=CC1=O)N1CCC(NCCOCCOCCNC(OC[C@H]2[C@@]3([H])[C@]2([H])CCC#CCC3)=O)=O

Molecular Formula

C24H33N3O7

Molecular Weight

475.53

Shipping Conditions

Room temperature

Scientific Category

ADC Related

Clinical Information

No Development Reported

Curated Selection

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