BCN-exo-PEG2-maleimide
BCN-exo-PEG2-maleimide is an ADC Linker containing 2 PEG units. BCN-exo-PEG2-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
Product Specifications
CAS Number
[2141976-22-7]
UNSPSC
12352203
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bcn-exo-peg2-maleimide.html
Solubility
10 mM in DMSO
Smiles
O=C(C=CC1=O)N1CCC(NCCOCCOCCNC(OC[C@H]2[C@@]3([H])[C@]2([H])CCC#CCC3)=O)=O
Molecular Formula
C24H33N3O7
Molecular Weight
475.53
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
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