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Hoechst 33342 analog trihydrochloride

Hoechst 33342 analog trihydrochloride is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore, Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1]. Storage: Keep away from light.

Product Specifications

CAS Number

[159277-19-7]

UNSPSC

12171500

Target

DNA Stain; Fluorescent Dye

Type

Dye Reagents

Related Pathways

Cell Cycle/DNA Damage; Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/hoechst-33342-analog-trihydrochloride.html

Solubility

10 mM in DMSO

Smiles

ClCCN(CCCl)C1=CC=C(CCCC2=NC3=C(N2)C=C(C4=NC5=C(N4)C=C(N6CCN(CC6)C)C=C5)C=C3)C=C1.[H]Cl.[H]Cl.[H]Cl

Molecular Formula

C32H40Cl5N7

Molecular Weight

699.97

References & Citations

[1]Chazotte B. Labeling nuclear DNA with hoechst 33342. Cold Spring Harb Protoc. 2011 Jan 1;2011 (1) :pdb.prot5557.

Shipping Conditions

Room temperature

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Curated Selection

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