Hoechst 33342 analog trihydrochloride
Hoechst 33342 analog trihydrochloride is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore, Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1]. Storage: Keep away from light.
Product Specifications
CAS Number
[159277-19-7]
UNSPSC
12171500
Target
DNA Stain; Fluorescent Dye
Type
Dye Reagents
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/hoechst-33342-analog-trihydrochloride.html
Solubility
10 mM in DMSO
Smiles
ClCCN(CCCl)C1=CC=C(CCCC2=NC3=C(N2)C=C(C4=NC5=C(N4)C=C(N6CCN(CC6)C)C=C5)C=C3)C=C1.[H]Cl.[H]Cl.[H]Cl
Molecular Formula
C32H40Cl5N7
Molecular Weight
699.97
References & Citations
[1]Chazotte B. Labeling nuclear DNA with hoechst 33342. Cold Spring Harb Protoc. 2011 Jan 1;2011 (1) :pdb.prot5557.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
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