Tubulin polymerization-IN-52
Tubulin polymerization-IN-52 (compound SC23) is a potent tubulin polymerization inhibitor, with an IC50 of 2.9 μM[1].
Product Specifications
CAS Number
2108615-05-8
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-polymerization-in-52.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=CC=C1C(N2)=O)[C@@H]2CC(NCCN3C4=CC=CC=C4N=C3C(F)(F)F)=O
Molecular Formula
C21H18F3N5O3
Molecular Weight
445.39
References & Citations
[1]Horgan MJ, et al. Identification of Novel β-Tubulin Inhibitors Using a Combined In Silico/In Vitro Approach. J Chem Inf Model. 2023 Sep 29.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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