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Tubulin polymerization-IN-52

Tubulin polymerization-IN-52 (compound SC23) is a potent tubulin polymerization inhibitor, with an IC50 of 2.9 μM[1].

Product Specifications

CAS Number

2108615-05-8

UNSPSC

12352005

Target

Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tubulin-polymerization-in-52.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=CC=CC=C1C(N2)=O)[C@@H]2CC(NCCN3C4=CC=CC=C4N=C3C(F)(F)F)=O

Molecular Formula

C21H18F3N5O3

Molecular Weight

445.39

References & Citations

[1]Horgan MJ, et al. Identification of Novel β-Tubulin Inhibitors Using a Combined In Silico/In Vitro Approach. J Chem Inf Model. 2023 Sep 29.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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