SDH-IN-9

SDH-IN-9 (compound Ip) is a potent inhibitor of Succinate Dehydrogenase. SDH-IN-9 shows fungicidal activity against Fusarium graminearum Schw with the EC50 of 0.93 μg/mL[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sdh-in-9.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CN(C)N=C1C(F)F)N(C(C)CSC2=NC3=C(F)C=C(F)C=C3S2)OC

Molecular Formula

C17H16F4N4O2S2

Molecular Weight

448.46

References & Citations

[1]Yin YM, et al. Discovery of Benzothiazolylpyrazole-4-Carboxamides as Potent Succinate Dehydrogenase Inhibitors through Active Fragment Exchange and Link Approach. J Agric Food Chem. 2023;71 (40) :14471-14482.