Rhizochalinin
Rhizochalinin (Rhiz) is a cytotoxic sphingolipid. Rhizochalinin (Rhiz) counteracts glioblastoma cell proliferation by inducing apoptosis, G2/M-phase cell cycle arrest, and inhibition of autophagy. Rhizochalinin (Rhiz) can be used for human glioblastoma research[1].
Product Specifications
CAS Number
321541-13-3
Product Name Alternative
Rhiz
UNSPSC
12352211
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rhizochalinin.html
Solubility
10 mM in DMSO
Smiles
N[C@@H]([C@@H](CCCCCCCC(CCCCCCCCCCCCCC[C@@H](O)[C@H](N)C)=O)O)C
Molecular Formula
C28H58N2O3
Molecular Weight
470.77
References & Citations
[1]yshlovoy SA, et al. Rhizochalinin Exhibits Anticancer Activity and Synergizes with EGFR Inhibitors in Glioblastoma In Vitro Models. Mol Pharm. 2023 Oct 2;20 (10) :4994-5005.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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