HDAC6-IN-21

HDAC6-IN-21 (compound 13) is airreversibleinhibitor of histonedeacetylase 6 (HDAC6) [1].

Product Specifications

CAS Number

[2920929-76-4]

UNSPSC

12352005

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hdac6-in-21.html

Purity

99.44

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(C1=CN=C(NCC2=CC=CC=C2)N=C1)NNC(C(F)F)=O

Molecular Formula

C14H13F2N5O2

Molecular Weight

321.28

References & Citations

[1]König B, et al. Difluoromethyl-1,3,4-oxadiazoles Are Selective, Mechanism-Based, and Essentially Irreversible Inhibitors of Histone Deacetylase 6. J Med Chem. 2023;66 (19) :13821-13837.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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