Sigma-2 Radioligand 1
Product Specifications
UNSPSC Description
Sigma-2 Radioligand 1 (compound 1) is a Sigma-2 selective ligand. Sigma-2 Radioligand 1 has good biodistribution in mice and good in vivo activity in rats. [18F] Modified Sigma-2 Radioligand 1 for visualization of tumors in micro-PET/CT imaging, exhibiting high tumor uptake and tumor-to-background ratio. Experiments show that Sigma-2 Radioligand 1 binds highly specifically in U87MG glioma xenografts[1].
Target Antigen
Sigma Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/sigma-2-radioligand-1.html
Solubility
10 mM in DMSO
Smiles
FCCN1C(N(C2=C1C=CC=C2)CCCCN3CCC4=C(C3)C=C(C(OC)=C4)OC)=O
Molecular Weight
427.51
References & Citations
[1]Wang T, et al. Development of a Highly Specific 18F-Labeled Radioligand for Imaging of the Sigma-2 Receptor in Brain Tumors. J Med Chem. 2023 Sep 13.. .
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-156124/Sigma-2-Radioligand-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-156124/
Clinical Information
No Development Reported
CAS Number
2860554-32-9
Curated Selection
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