2-Chlorophenoxazine
Product Specifications
UNSPSC Description
2-Chlorophenoxazine is a Akt inhibitor with an IC50 value of 2-5 μM for in vitro. 2-Chlorophenoxazine can induce apoptosis. 2-Chlorophenoxazine can be used for cancer diseases research[1].
Target Antigen
Akt; Apoptosis
Type
Reference compound
Related Pathways
Apoptosis;PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-chlorophenoxazine.html
Solubility
10 mM in DMSO
Smiles
ClC(C=C1N2)=CC=C1OC3=C2C=CC=C3
Molecular Weight
217.65
References & Citations
[1]Thimmaiah KN, et al. Identification of N10-substituted phenoxazines as potent and specific inhibitors of Akt signaling. J Biol Chem. 2005 Sep 9;280(36):31924-35
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-156108/2-Chlorophenoxazine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-156108/
Clinical Information
No Development Reported
CAS Number
56821-03-5
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