2-Chlorophenoxazine

2-Chlorophenoxazine is a Akt inhibitor with an IC50 value of 2-5 μM for in vitro. 2-Chlorophenoxazine can induce apoptosis. 2-Chlorophenoxazine can be used for cancer diseases research[1].

Product Specifications

CAS Number

[56821-03-5]

UNSPSC

12352005

Target

Akt; Apoptosis

Type

Reference compound

Related Pathways

Apoptosis; PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/2-chlorophenoxazine.html

Solubility

10 mM in DMSO

Smiles

ClC(C=C1N2)=CC=C1OC3=C2C=CC=C3

Molecular Formula

C12H8ClNO

Molecular Weight

217.65

References & Citations

[1]Thimmaiah KN, et al. Identification of N10-substituted phenoxazines as potent and specific inhibitors of Akt signaling. J Biol Chem. 2005 Sep 9;280 (36) :31924-35