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RyRs activator 3

RyRs activator 3 (compound A4) is an effective insecticide against diamondback moths (M. separata) and diamondback moths (P. xylostella) . The LC50 value of RyRs activator 3 against diamondback moth is 3.27 mg/L. RyRs activator 3 can bind to ryanodine receptor, increase cytoplasmic Ca2+ concentration, and produce biological toxicity[1].

Product Specifications

CAS Number

[2850333-35-4]

UNSPSC

12352005

Target

Calcium Channel; Parasite

Type

Reference compound

Related Pathways

Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ryrs-activator-3.html

Solubility

10 mM in DMSO

Smiles

BrC1=NN(C(C(NC2=C(C=C(C=C2C3=NOC(C3)C(NC4CC4)=O)Cl)C)=O)=C1)C5=NC=CC=C5Cl

Molecular Formula

C23H19BrCl2N6O3

Molecular Weight

578.25

References & Citations

[1]Pang X, et al. Design, Synthesis, and Insecticidal Evaluation of N-Pyridylpyrazole Amide Derivatives Containing 4,5-Dihydroisoxazole Amide as Potential Ryanodine Receptor Activators. J Agric Food Chem. 2023 Sep 20;71 (37) :13688-13695. .

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-156082/RyRs-activator-3-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-156082/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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