anti-TNBC agent-2
Product Specifications
UNSPSC Description
anti-TNBC agent-2 (3j) an anti-Triple negative breast cancer (TNBC) purine derivative. anti-TNBC agent-2 induces MDA-MB-231 cells apoptosis, and inhibits its migration and angiogenesis. anti-TNBC agent-2 inhibits tumor growth and metastasis and reduces the expression of Ki67 and CD31 protein in TNBC xenograft models. anti-TNBC agent-2 can be used for Triple negative breast cancer (TNBC) research[1].
Target Antigen
Apoptosis; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Apoptosis;Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anti-tnbc-agent-2.html
Solubility
10 mM in DMSO
Smiles
FC1=CC=C(C=C1Cl)CNC2=C3N=CN(C3=NC(N4CCC(CC4)C5CCN(CC5)CCO)=N2)CC6CC6
Molecular Weight
542.09
References & Citations
[1]Zhang Q, et al. Synthesis and mechanism of action of new purine derivatives against triple negative breast cancer. Eur J Med Chem. 2023 Sep 7;261:115797.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-156077/anti-TNBC-agent-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-156077/
Clinical Information
No Development Reported
CAS Number
9007-83-4
Curated Selection
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