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IA1-8H2

IA1-8H2 is a non-covalent, non-competitive inhibitor of PHPT1 (IC50: 3.4 μM) . IA1-8H2 can be used for research of lung cancer, hepatocarcinoma, and renal cancer[1].

Product Specifications

CAS Number

2755685-19-7

UNSPSC

12352005

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ia1-8h2.html

Solubility

10 mM in DMSO

Smiles

OC(CC1=C2C3=C(CCC3)C(O)=C1C=O)OC2=O

Molecular Formula

C13H12O5

Molecular Weight

248.23

References & Citations

[1]Wang H, et al. Derivatives of the Fungal Natural Product Illudalic Acid Inhibit the Activity of Protein Histidine Phosphatase PHPT1. ChemMedChem. 2023 Aug 1;18 (15) :e202300187.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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