IA1-8H2
IA1-8H2 is a non-covalent, non-competitive inhibitor of PHPT1 (IC50: 3.4 μM) . IA1-8H2 can be used for research of lung cancer, hepatocarcinoma, and renal cancer[1].
Product Specifications
CAS Number
2755685-19-7
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ia1-8h2.html
Solubility
10 mM in DMSO
Smiles
OC(CC1=C2C3=C(CCC3)C(O)=C1C=O)OC2=O
Molecular Formula
C13H12O5
Molecular Weight
248.23
References & Citations
[1]Wang H, et al. Derivatives of the Fungal Natural Product Illudalic Acid Inhibit the Activity of Protein Histidine Phosphatase PHPT1. ChemMedChem. 2023 Aug 1;18 (15) :e202300187.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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