FIKK9.1-IN-1

FIKK9.1-IN-1 (Compound 1) is a FIKK9.1 inhibitor. FIKK9.1-IN-1 interacts with the ATP binding residues in FIKK9.1. FIKK9.1-IN-1 is an antimalarial agent (IC50: 2.68 μg/mL) and disrupts the parasite life cycle and leads to the death of parasites[1].

Product Specifications

CAS Number

[1448523-50-9]

UNSPSC

12352005

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/fikk9-1-in-1.html

Solubility

10 mM in DMSO

Smiles

CC(N1CC([Se]/C1=N\C2=CC=CC3=C2C=CC=C3)C4=CC=CC=C4)C

Molecular Formula

C22H22N2Se

Molecular Weight

393.38

References & Citations

[1]Kumar DA, et al. Plasmodium falciparum FIKK 9.1 kinase modeling to screen and identify potent antimalarial agents from chemical library. 3 Biotech. 2023 Aug;13 (8) :277.