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TEAD-IN-6

TEAD-IN-6 (Example 11-1) is a TEAD modulator that blocks the interaction between YAP1/TAZ and TEAD. TEAD-IN-6 can be used in cancer research[1].

Product Specifications

CAS Number

2821763-12-4

UNSPSC

12352005

Target

YAP

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/tead-in-6.html

Solubility

10 mM in DMSO

Smiles

O=S(C1=CC(C2=CN3C(CCC3)=N2)=C(OC4=CC=C(C(F)(F)F)C=C4)N=C1)(NC)=O

Molecular Formula

C19H17F3N4O3S

Molecular Weight

438.42

References & Citations

[1]Jongwon Lim, et al. Aryl ether compounds as tead modulators. Patent WO2022177869A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

YAP/TAZ-TEAD

Frequently Asked Questions

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