TEAD-IN-6
TEAD-IN-6 (Example 11-1) is a TEAD modulator that blocks the interaction between YAP1/TAZ and TEAD. TEAD-IN-6 can be used in cancer research[1].
Product Specifications
CAS Number
2821763-12-4
UNSPSC
12352005
Target
YAP
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/tead-in-6.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC(C2=CN3C(CCC3)=N2)=C(OC4=CC=C(C(F)(F)F)C=C4)N=C1)(NC)=O
Molecular Formula
C19H17F3N4O3S
Molecular Weight
438.42
References & Citations
[1]Jongwon Lim, et al. Aryl ether compounds as tead modulators. Patent WO2022177869A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
YAP/TAZ-TEAD
Frequently Asked Questions
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