DUB-IN-7
DUB-IN-7 (compound 43) is a Deubiquitinating enzymes (DUBs) inhibitor. DUB-IN-7 can be used in the study of diseases mediated by dysregulated JAK2 activity, such as leukemia[1].
Product Specifications
CAS Number
2894064-79-8
UNSPSC
12352005
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dub-in-7.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H]1CN(CCC1)C#N)NC(N=C2)=CN2CC3=CC=CC=C3
Molecular Formula
C17H19N5O
Molecular Weight
309.37
References & Citations
[1]Sara BUHRLAGE, et al. Small molecule inhibition of deubiquitinating enzyme josephin domain containing 1 (josd1) as a targeted therapy for leukemias with mutant janus kinase 2 (jak2) . Patent WO2023009982A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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