Anti-inflammatory agent 56
Product Specifications
UNSPSC Description
Anti-inflammatory agent 56 (Compound 9) is a selective COX-2 inhibitor (IC50: 0.54 μM). Anti-inflammatory agent 56 has anti-oxidant and anti-inflammatory effects. Anti-inflammatory agent 56 inhibits oxidative stress induced cell death. Anti-inflammatory agent 56 inhibits oxidative stress and neuroinflammation by inhibiting Keap1, COX-2 and iNOS. Anti-inflammatory agent 56 has low acute toxicity in mice (LD50: 1000 mg/kg)[1].
Target Antigen
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-inflammatory-agent-56.html
Solubility
10 mM in DMSO
Smiles
O=S(N)(C1=CC=C(N2N=C(C3=C(O)C=C(C(F)(F)F)C=C3)N=C2C4=C(O)C=CC=C4)C=C1)=O
Molecular Weight
476.43
References & Citations
[1]Wang Y, et al. Synthesis of 1,3,5-triphenyl-1,2,4-triazole derivatives and their neuroprotection by anti-oxidative stress and anti-inflammation and protecting BBB. Eur J Med Chem. 2023 Nov 15;260:115742.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-155997/Anti-inflammatory-agent-56-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-155997/
Clinical Information
No Development Reported
CAS Number
9007-83-4
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