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E07 aptamer

E07 aptamer is an aptamer that targets human EGFR. E07 aptamer can compete with EGF for binding, binds to a novel epitope on EGFR. E07 aptamer binds to cells expressing EGFR, blocks receptor autophosphorylation, and prevents proliferation of tumor cells in three-dimensional matrices. E07 aptamer can be used for tomor disease research[1].

Product Specifications

UNSPSC

12352100

Target

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/e07-aptamer.html

Solubility

10 mM in DMSO

Smiles

[5'-GGACGGAUUUAAUCGCCGUAGAAAAGCAUGUCAAAGCCGGAACCGUCC-3']

References & Citations

[1]Li N, et al. Inhibition of cell proliferation by an anti-EGFR aptamer. PLoS One. 2011;6 (6) :e20299. doi: 10.1371/journal.pone.0020299. Epub 2011 Jun 8.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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