E07 aptamer
E07 aptamer is an aptamer that targets human EGFR. E07 aptamer can compete with EGF for binding, binds to a novel epitope on EGFR. E07 aptamer binds to cells expressing EGFR, blocks receptor autophosphorylation, and prevents proliferation of tumor cells in three-dimensional matrices. E07 aptamer can be used for tomor disease research[1].
Product Specifications
UNSPSC
12352100
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e07-aptamer.html
Solubility
10 mM in DMSO
Smiles
[5'-GGACGGAUUUAAUCGCCGUAGAAAAGCAUGUCAAAGCCGGAACCGUCC-3']
References & Citations
[1]Li N, et al. Inhibition of cell proliferation by an anti-EGFR aptamer. PLoS One. 2011;6 (6) :e20299. doi: 10.1371/journal.pone.0020299. Epub 2011 Jun 8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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