SARS-CoV-2 3CLpro-IN-18
SARS-CoV-2 3CLpro-IN-18 (Compound 3C) is a covalent SARS-CoV-2 3CLpro inhibitor (IC50s: 0.478 μM) . SARS-CoV-2 3CLpro-IN-18 inhibits SARS-CoV-2 in Vero E6 cells (EC50= 2.499 μM) with low cytotoxicity (CC50 > 200 μM) [1].
Product Specifications
CAS Number
[3032604-29-5]
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sars-cov-2-3clpro-in-18.html
Solubility
10 mM in DMSO
Smiles
O=C(N1C2=CC(Cl)=CC=C2CCC3=CC=CC=C31)CSC#N
Molecular Formula
C17H13ClN2OS
Molecular Weight
328.82
References & Citations
[1]Ren P, et al. Discovery and Mechanism Study of SARS-CoV-2 3C-like Protease Inhibitors with a New Reactive Group. J Med Chem. 2023 Aug 18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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