SARS-CoV-2 3CLpro-IN-18
SARS-CoV-2 3CLpro-IN-18 (Compound 3C) is a covalent SARS-CoV-2 3CLpro inhibitor (IC50s: 0.478 μM) . SARS-CoV-2 3CLpro-IN-18 inhibits SARS-CoV-2 in Vero E6 cells (EC50= 2.499 μM) with low cytotoxicity (CC50 > 200 μM) [1].
Product Specifications
CAS Number
[3032604-29-5]
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sars-cov-2-3clpro-in-18.html
Solubility
10 mM in DMSO
Smiles
O=C(N1C2=CC(Cl)=CC=C2CCC3=CC=CC=C31)CSC#N
Molecular Formula
C17H13ClN2OS
Molecular Weight
328.82
References & Citations
[1]Ren P, et al. Discovery and Mechanism Study of SARS-CoV-2 3C-like Protease Inhibitors with a New Reactive Group. J Med Chem. 2023 Aug 18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS2059222-01 0.1 mL
APC/CY7-Linked Polyclonal Antibody to Signal Transducer And Activator Of Transcription 2 (STAT2)
Ask
View Details 
MBS2059222-02 0.2 mL
APC/CY7-Linked Polyclonal Antibody to Signal Transducer And Activator Of Transcription 2 (STAT2)
Ask
View Details 
MBS2059222-03 0.5 mL
APC/CY7-Linked Polyclonal Antibody to Signal Transducer And Activator Of Transcription 2 (STAT2)
Ask
View Details MBS2059222-04 1 mL
APC/CY7-Linked Polyclonal Antibody to Signal Transducer And Activator Of Transcription 2 (STAT2)
Ask
View Details MBS2059222-05 5 mL
APC/CY7-Linked Polyclonal Antibody to Signal Transducer And Activator Of Transcription 2 (STAT2)
Ask
View Details MBS2059222-06 5x 5 mL
APC/CY7-Linked Polyclonal Antibody to Signal Transducer And Activator Of Transcription 2 (STAT2)
Ask
View Details