Urease-IN-8
Urease-IN-8 (Compound 5e) is a competitive Urease inhibitor (IC50: 3.51 μM, Ki: 3.11 μM) . Urease-IN-8 can be used for research of peptic and gastric ulcers[1].
Product Specifications
CAS Number
517906-16-0
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/urease-in-8.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(C=C1)C2=NN=C3SCC(C4=CC=C(C5=CC=CC=C5)C=C4)=NN23
Molecular Formula
C23H18N4OS
Molecular Weight
398.48
References & Citations
[1]Jalal Uddin, et al. Triazolothiadiazoles and Triazolothiadiazines as New and Potent Urease Inhibitors: Insights from In Vitro Assay, Kinetics Data, and In Silico Assessment. ACS Omega 2023, 8, 35, 31890?1898.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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