What is the catalog number for Phen-DC3?

The catalog number for Phen-DC3 is HY-15594.

What sizes are available for Phen-DC3?

Phen-DC3 is available in the following size(s): 1 Each.

Is Phen-DC3 in stock?

Phen-DC3 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Phen-DC3?

Phen-DC3 is manufactured by QuantiMol.

What is the estimated delivery time for Phen-DC3?

Estimated delivery time for Phen-DC3 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Phen-DC3?

The safety data sheet for Phen-DC3 is available here: http://file.medchemexpress.com/batch_PDF/HY-15594/.

Phen-DC3

Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases with IC50s of 65±6 and 50±10 nM, respectively.

Product Specifications

CAS Number

942936-75-6

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Phen-DC3.html

Solubility

DMSO : ≥ 34 mg/mL

Smiles

C[N+]1=C2C=CC=CC2=CC(NC(C3=CC=C4C=CC5=CC=C(C(NC6=C[N+](C)=C7C=CC=CC7=C6)=O)N=C5C4=N3)=O)=C1

Molecular Formula

C34H26N6O2

Molecular Weight

550.61

References & Citations

[1]Bharti SK, et al. Specialization among iron-sulfur cluster helicases to resolve G-quadruplex DNA structures that threaten genomic stability. J Biol Chem. 2013 Sep 27; 288 (39) :28217-29.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Citation 01

J Phys Chem B. 2023 Jul 6;127 (26) :5859-5868.|Nucleic Acids Res. 2024 Mar 21;52 (5) :2142-2156.|Patent. US20210188889A1.|Cell Death Dis. 2021 Oct 25;12 (11) :999.|Int J Biol Macromol. 2025 Jan 9:139582.|Int J Biol Macromol. 2025 Jun 20;319 (Pt 1) :145405.|iScience. 2022 Oct 9;25 (11) :105312.