DSPE-PEG-Amine, MW 5000 (ammonium)

DSPE-PEG-Amine, MW 5000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. DSPE-PEG-Amine, MW 5000 (ammonium) amino group can be converted to aromatic aldehydes that react with acetone-protected aromatic hydrazides on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes produce liposome-Bah-BCA conjugates by forming diaryl hydrazone (BAH) with target enzyme molecules. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

Product Specifications

CAS Number

[474922-26-4]

Product Name Alternative

DSPE-PEG-NH2, MW 5000 (ammonium)

UNSPSC

12352200

Hazard Statement

H302-H315-H319-H335

Target

Liposome

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dspe-peg-amine-mw-5000-ammonium.html

Solubility

10 mM in DMSO

Smiles

O=C(O[C@@H](COP(OCCNC(OCCOCCN)=O)([O-])=O)COC(CCCCCCCCCCCCCCCCC)=O)CCCCCCCCCCCCCCCCC.[NH4+].[n]

Molecular Formula

(C2H4O) nC44H87N2O10P.NH3

Molecular Weight

5000 (Average)

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Nagata H, et al. Preparation and Catalytic Properties of Carbonic Anhydrase Conjugated to Liposomes through a Bis-Aryl Hydrazone Bond. ACS Omega. 2023 May 16;8 (21) :18637-18652.